1.
Enfermedad de Hirschprung: avances en el diagnóstico / Hirschsprung's disease: advances in diagnosis
Rev. pediatr. electrón
;
13(2): 13-18, ago. 2016.
Article
in Spanish
| LILACS
| ID: biblio-869932
2.
Pediatría (Santiago de Chile)
;
5(1)2008.
Article
in Spanish
| LILACS
| ID: lil-486854
3.
Acta méd. (Porto Alegre)
;
28: 116-125, 2007.
Article
in Portuguese
| LILACS
| ID: lil-478559
ABSTRACT
Os autores fazem uma revisão sobre a Doença de Hirschsprung, sua etiologia, diagnóstico e tratamento.
Subject(s)
Humans , Male , Female , Hirschsprung Disease/surgery , Hirschsprung Disease/diagnosis , Hirschsprung Disease/etiology
4.
Journal of Huazhong University of Science and Technology (Medical Sciences)
;
(6): 152-4, 2002.
Article
in English
| WPRIM
| ID: wpr-634044
ABSTRACT
In order to investigate the relationship between the expression of heme oxygenase-2 (HO-2) mRNA and the pathogenesis of Hirschsprung's disease (HD), total ribonucleic acid (RNA) was extracted in the aganglionic and ganglionic segments of colon respectively from 15 cases of HD. The single-stranded cDNA of HO-2 was synthesized and further amplified by reverse transcription-polymerase chain reaction (RT-PCR). The expression of HO-2 mRNA was normal in ganglionic segments, but absent in aganglionic segments. It is concluded that the absence of HO-2 mRNA expression may be an important mechanism responsible for HD.